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KMID : 0371320010600030331
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Journal of the Korean Surgical Society
2001 Volume.60 No. 3 p.331 ~ p.336
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Surgical Treatment of Intestinal Behcet’s Disease
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Kim Nam-Ryeol
Whang Jeong-Woong
Um Jun-Won
Moon Hong-Young
Bae Jung-Won
Seo Seong-Ok
Jung Suk-In
Joh Yong-Geul
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Abstract
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Purpose: No standardized treatment protocol yet exists for intestinal Behcet’s disease. The aim of this retrospective study was to identify the factors that are related to the recurrence and mortality of intestinal Behcet’s disease.
Methods: Twelve patients who had undergone surgery for intestinal Behcet’s disease at Korea University Hospital from 1991 to 1999 were chosen. Nineteen patients had been diagnosed as having intestinal Behcet’s disease. Of the 19 patients, 7 are still being followed up, and 12 have undergone surgery, these patients were chosen as the subjects.
Results: Of the 11 cases, excluding one case that expired following the initial surgery, 8 cases required subsequent surgery due to recurrence. When the data was analyzed according to the patient’s age, medication, clas sification of Behcet’s disease, location of the lesion, operative method, and extent of resection, recurrence was shown to be related with medication and extent of resection (p＜0.05). Of the 12 cases, 5 cases expired. When, the data of the 5 cases that expired were analyzed according to the patient’s age, medication, extent of resection, classification of Behcet’s disease, location of the lesion, and operative method, mortality was shown to be related with the location of the lesion (p＜0.05).
Conclusion: Medical treatment is the primary therapy for intestinal Behcet’s disease and radical extended resection extending 30 cm proximal and distal to the lesion prevents recurrence. However, when the lesion was located in the small intestine and formed a fistula with the duodenum, the prognosis appears to be extremely poor.
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KEYWORD
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Intestinal Behcet’s disease, Prognostic factor, Surgical resection cases
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